Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 14/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 14/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 10/20 | 0.44 |
| ▸ | IGF1R | P08069 | 5/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ponazuril SCHEMBL29625926 | 0.89 | NTRK1 (0.55) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| Ponazuril SCHEMBL203030 | 0.89 | NTRK1 (0.55) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10527532 | 0.88 | NTRK1 (0.55) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL11474624 | 0.88 | NTRK1 (0.56) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10528041 | 0.88 | EPAS1 (0.44) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10527978 | 0.86 | NTRK1 (0.49) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL11490392 | 0.85 | NTRK1 (0.41) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL11478539 | 0.84 | NTRK1 (0.45) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10527351 | 0.83 | BRAF (0.35) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL11479080 | 0.81 | NTRK1 (0.44) | NTRK1NTRK2NTRK3IGF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219552-A | AND HAVING GOOD COCCIDIOSTATIC ACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-26 | — | — | US | disclosed |