Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 15/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 15/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 11/20 | 0.45 |
| ▸ | IGF1R | P08069 | 5/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.43 |
| ▸ | BRAF | P15056 | 4/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toltrazuril SCHEMBL29509205 | 0.88 | NTRK1 (0.57) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| Toltrazuril SCHEMBL248912 | 0.88 | NTRK1 (0.57) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| Toltrazuril SCHEMBL21812043 | 0.88 | NTRK1 (0.57) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10525684 | 0.88 | NTRK1 (0.58) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10525747 | 0.85 | NTRK1 (0.51) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL11477300 | 0.85 | NTRK1 (0.60) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL11475552 | 0.84 | NTRK1 (0.44) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| Toltrazuril SCHEMBL19436333 | 0.81 | NTRK1 (0.49) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL13780159 | 0.81 | NTRK1 (0.48) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10975351 | 0.80 | NTRK1 (0.52) | NTRK1NTRK2NTRK3IGF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219552-A | AND HAVING GOOD COCCIDIOSTATIC ACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-26 | — | — | US | disclosed |