Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL11533802 | 0.92 | KMT2A (0.39) | KMT2AMAPTSSTR4KCNN4LMNA | |
| Fumaric Acid SCHEMBL11533801 | 0.92 | KMT2A (0.39) | KMT2AMAPTSSTR4KCNN4LMNA | |
| SCHEMBL953947 | 0.87 | KMT2A (0.50) | KMT2AMAPTSSTR4KCNN4LMNA | |
| SCHEMBL4396455 | 0.87 | KMT2A (0.50) | KMT2AMAPTSSTR4KCNN4LMNA | |
| SCHEMBL958241 | 0.87 | KMT2A (0.50) | KMT2AMAPTSSTR4KCNN4LMNA | |
| Bromide SCHEMBL4505514 | 0.85 | KMT2A (0.49) | KMT2AMAPTSSTR4KCNN4LMNA | |
| Bromide SCHEMBL4505510 | 0.85 | KMT2A (0.49) | KMT2AMAPTSSTR4KCNN4LMNA | |
| Hydrochloric Acid SCHEMBL10869034 | 0.85 | KMT2A (0.49) | KMT2AMAPTSSTR4KCNN4LMNA | |
| SCHEMBL8424910 | 0.84 | KEAP1 (0.43) | KMT2AMAPTLMNAMEN1CYP2D6 | |
| SCHEMBL5808342 | 0.84 | KEAP1 (0.43) | KMT2AMAPTLMNAMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133881-A | Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods | A. H. ROBINS COMPANY, INCORPORATED (US) | 1979-01-09 | — | — | US | claimed |
| US-4242261-A | REACTING AN A,A-DIPHENYL-A-N-HETEROCYCLIC ACETAMIDE WITH BROMINE AND AN ALKALI METAL ALKOXIDE AND HEATING | A. H. ROBINS COMPANY, INC. (US) | 1980-12-30 | — | — | US | disclosed |