Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475788 | 1.00 | MEN1 (0.44) | MEN1KMT2ACYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10963096 | 0.89 | MEN1 (0.38) | MEN1KMT2ACYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10963100 | 0.89 | MEN1 (0.38) | MEN1KMT2ACYP2C19CYP1A2CYP3A4 | |
| SCHEMBL7694807 | 0.85 | LMNA (0.39) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL11807943 | 0.79 | ALDH1A1 (0.34) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL3603249 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL3607061 | 0.77 | ALDH1A1 (0.39) | MEN1KMT2ACYP2C19TSHRALDH1A1 | |
| SCHEMBL9190299 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL10870370 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL10870379 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2ACYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189431-A | CYCLIZATION OF POLYENINE TO POLYCYCLIC COMPOUND HAVING CYCLOPENTANO RING | The Board of Trustees of Leland Stanford Junior University (US) | 1980-02-19 | — | — | US | disclosed |
| US-4129599-A | A-Norsteroids | THE BOARD OF TRUSTEES OF LELAND STANFORD JR. UNIVERSITY (US) | 1978-12-12 | — | — | US | disclosed |
| US-4064185-A | Olefinically unsaturated substituents at C-11 of steroid cyclization precursors | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4055603-A | HORMONES | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4032579-A | POLY-UNSATURATED HYDROXY-ALKYNYL CYCLOPENTENOL | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 1977-06-28 | — | — | US | disclosed |