Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694807 | 0.92 | LMNA (0.39) | ALDH1A1LMNAHSD17B10FNTAFNTB | |
| SCHEMBL11774659 | 0.88 | CYP2D6 (0.40) | ALDH1A1LMNAHSD17B10FNTAFNTB | |
| SCHEMBL11130468 | 0.87 | GLO1 (0.40) | ALDH1A1LMNAHSD17B10FNTAFNTB | |
| SCHEMBL10837285 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GLO1GRIK1 | |
| SCHEMBL4740790 | 0.80 | FNTA (0.41) | ALDH1A1FNTAFNTBGRIK1GRIK2 | |
| SCHEMBL8990247 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL5142671 | 0.79 | GRIK1 (0.46) | ALDH1A1LMNAHSD17B10GLO1GRIK1 | |
| SCHEMBL28127614 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10GLO1GRIK1 | |
| SCHEMBL9040524 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLO1CYP2D6 | |
| SCHEMBL10963096 | 0.76 | MEN1 (0.38) | ALDH1A1LMNAHSD17B10FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737504-B2 | Dihydroorotic and acid dehydrogenase inhibitor | INSTITUTE OF MITOCHONDRIA SCIENCE, INC. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9737504-B2 | Dihydroorotic and acid dehydrogenase inhibitor | INSTITUTE OF MITOCHONDRIA SCIENCE, INC. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160296494-A1 | DIHYDROOROTIC AND ACID DEHYDROGENASE INHIBITOR | NAI INC. | 2016-10-13 | — | — | US | disclosed |
| US-20160296494-A1 | DIHYDROOROTIC AND ACID DEHYDROGENASE INHIBITOR | NAI INC. | 2016-10-13 | — | — | US | disclosed |
| US-9440913-B2 | Dihydroxybenzene derivatives and antiprotozoal agent comprising same as active ingredient | NAI INC. (JP) | 2016-09-13 | — | — | US | disclosed |
| US-9440913-B2 | Dihydroxybenzene derivatives and antiprotozoal agent comprising same as active ingredient | NAI INC. (JP) | 2016-09-13 | — | — | US | disclosed |
| US-20150166498-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | NAI INC. (JP) | 2015-06-18 | — | — | US | disclosed |
| US-20150166498-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | NAI INC. (JP) | 2015-06-18 | — | — | US | disclosed |
| EP-2857010-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | NAI Inc. (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-20130296422-A1 | Novel Dihydroxybenzene Derivatives and Antiprotozoal Agent Comprising Same as Active Ingredient | ARIGEN PHARMACEUTICALS, INC. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-4484000-A | PHOTOGRAPHIC STABILIZERS | CIBA-GEIGY AG (CH) | 1984-11-20 | — | — | US | disclosed |
| EP-0069068-B1 | HYDROQUINONES AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |
| US-4466969-A | 7-Oxoprostacyclin derivatives and their use as hypotensives and bronchodilators | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-21 | — | — | US | disclosed |
| EP-0106799-A1 | Phenols and their preparation | CIBA-GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| US-4430425-A | HYDROQUINONE DERIVATIVES | CIBA-GEIGY AG (CH) | 1984-02-07 | — | — | US | disclosed |
| EP-0069070-A1 | Colour photographic materials containing stabilizers | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |
| US-4359467-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| EP-0059756-A1 | 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF. | SCHERING AG (DE) | 1982-09-15 | — | — | EP | disclosed |
| WO-1982001002-A1 | 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | NICKOLSON R | 1982-04-01 | — | — | WO | disclosed |
| US-4284646-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166498-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | DHODH, DPYD, DLD | ALDH1A1 93/4885LMNA 4866/4885HSD17B10 38/4885 |
| US-20130296422-A1 | Novel Dihydroxybenzene Derivatives and Antiprotozoal Agent Comprising Same as Active Ingredient | CBR3, CBR1, DHX35 | ALDH1A1 1072/4885LMNA 3363/4885HSD17B10 423/4885 |
| US-20160296494-A1 | DIHYDROOROTIC AND ACID DEHYDROGENASE INHIBITOR | DHODH, DPYD, DLD | ALDH1A1 75/4885LMNA 4867/4885HSD17B10 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.