SCHEMBL11475883

SCHEMBL11475883

CCOC(=O)C(N)CC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 4/20 0.34
GAA P10253 3/20 0.34
KDM4E B2RXH2 3/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 2/20 0.31
RECQL P46063 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
ALOX15 P16050 2/20 0.31
METAP2 P50579 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11391382 0.83 ALDH1A1 (0.36) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL28270788 0.78 L3MBTL1 (0.39) ALDH1A1GAATSHRALOX15METAP2
SCHEMBL8201307 0.78 ALDH1A1 (0.37) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL11485398 0.76 GAA (0.36) MEN1KMT2APOLBGAAKDM4E
SCHEMBL1066592 0.75 METAP2 (0.42) GAATSHRALOX15METAP2
SCHEMBL20543740 0.75 METAP2 (0.45) ALDH1A1NPSR1TSHRMETAP2LMNA
SCHEMBL28785091 0.75 METAP2 (0.42) GAATSHRALOX15METAP2
SCHEMBL16710262 0.73 GAA (0.39) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL13836892 0.73 METAP2 (0.47) ALDH1A1NPSR1TSHRMETAP2
SCHEMBL21118051 0.73 METAP2 (0.47) ALDH1A1NPSR1TSHRMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4223147-A POLYMER STABILIZERS BAYER AKTIENGESELLSCHAFT (DE) 1980-09-16 US disclosed
US-4153596-A PHOTOSTABILITY BAYER AKTIENGESELLSCHAFT (DE) 1979-05-08 US disclosed