Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.68 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591740 | 1.00 | SIGMAR1 (0.68) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL18408128 | 0.83 | OPRM1 (0.66) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL1206273 | 0.83 | OPRM1 (0.66) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL13014950 | 0.81 | SIGMAR1 (1.00) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL11593513 | 0.81 | SIGMAR1 (0.46) | SIGMAR1OPRK1OPRM1OPRD1TMEM97 | |
| SCHEMBL11710419 | 0.81 | SIGMAR1 (1.00) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL972352 | 0.81 | SIGMAR1 (1.00) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL1299748 | 0.81 | SIGMAR1 (1.00) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL11487059 | 0.81 | OPRD1 (0.71) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 | |
| SCHEMBL14619144 | 0.81 | SIGMAR1 (1.00) | SIGMAR1OPRK1OPRM1OPRD1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205171-A | ANALGESICS | STERLING DRUG INC. (US) | 1980-05-27 | — | — | US | disclosed |
| US-RE29943-E | ANALGESICS | STERLING DRUG INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4127577-A | Aminomethanobenzazocine process | STERLING DRUG INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4108857-A | CNS DEPRESSANTS, ANALGESICS, PSYCHOMOTOR ACTION | STERLING DRUG INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4032529-A | ANALGESICS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-3968114-A | ANALGESIC | STERLING DRUG INC. (US) | 1976-07-06 | — | — | US | disclosed |
| US-3957793-A | ANALGESICS | STERLING DRUG INC. (US) | 1976-05-18 | — | — | US | disclosed |