Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190319 | 0.80 | ALDH1A1 (0.43) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL27461969 | 0.80 | ALDH1A1 (0.43) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL17937229 | 0.80 | CHRNB2 (0.38) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL16998487 | 0.79 | AAK1 (0.38) | AAK1MMP13CA1CA2CA7 | |
| SCHEMBL7397930 | 0.78 | POLB (0.36) | AAK1MMP13CA14 | |
| SCHEMBL21258087 | 0.77 | AAK1 (0.36) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL17618251 | 0.77 | AAK1 (0.36) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL8994031 | 0.77 | ALDH1A1 (0.40) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL20061836 | 0.77 | EPHX2 (0.35) | AAK1MMP13CTSSCTSKCA14 | |
| SCHEMBL23976692 | 0.76 | POLB (0.36) | AAK1MMP13CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019411-A1 | 1-Phenyl-2-aminoethanol derivatives, processes for their manufacture and pharmaceutical compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-11-26 | — | — | EP | disclosed |