Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061836 | 0.87 | EPHX2 (0.35) | MEN1KMT2AALDH1A1AAK1CA14 | |
| SCHEMBL17937229 | 0.85 | CHRNB2 (0.38) | MEN1KMT2AAAK1CA14USP2 | |
| SCHEMBL27461969 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTAAK1 | |
| SCHEMBL8190319 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTAAK1 | |
| SCHEMBL15585241 | 0.78 | CA14 (0.36) | MEN1KMT2AAAK1CA14MMP13 | |
| SCHEMBL16443932 | 0.78 | CA14 (0.36) | MEN1KMT2AAAK1CA14MMP13 | |
| SCHEMBL11476293 | 0.78 | AAK1 (0.37) | AAK1CA14MMP13 | |
| SCHEMBL12344713 | 0.78 | ADRB2 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22525146 | 0.76 | AAK1 (0.34) | AAK1CA14 | |
| SCHEMBL17618251 | 0.76 | AAK1 (0.36) | AAK1CA14MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036404-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-25 | — | — | WO | disclosed |