Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TET3 | O43151 | 2/20 | 0.42 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.42 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.42 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258115 | 0.86 | RHEB (0.44) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL11257926 | 0.79 | ALDH1A1 (0.48) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL11248843 | 0.77 | ALDH1A1 (0.42) | KMT2ALMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11479620 | 0.77 | CCR8 (0.44) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL11248404 | 0.74 | SMN1; SMN2 (0.43) | KDM4ELMNAALDH1A1HTR1AHTR3A | |
| SCHEMBL11484877 | 0.72 | MEN1 (0.46) | KMT2AHSD11B1KDM4ELMNAALDH1A1 | |
| SCHEMBL11253946 | 0.72 | ALDH1A1 (0.46) | KMT2AKDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL11490169 | 0.71 | ALDH1A1 (0.47) | KMT2AKDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL27381366 | 0.71 | KMT2A (0.65) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL11253111 | 0.71 | HTR1A (0.43) | KMT2AKDM4ELMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |