Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476261 | 0.89 | LMNA (0.44) | LMNAALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL11516242 | 0.85 | MEN1 (0.43) | LMNAALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL13505997 | 0.74 | NAMPT (0.48) | NAMPTGRM5MAPK1PRMT5WDR77 | |
| SCHEMBL11516079 | 0.71 | LMNA (0.45) | LMNAALDH1A1NAMPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11516834 | 0.70 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL12563463 | 0.70 | PIK3R1 (0.35) | NAMPTGRM5PRMT5WDR77HRH3 | |
| SCHEMBL12082592 | 0.69 | NAMPT (0.38) | NAMPTGRM5PRMT5WDR77HRH3 | |
| SCHEMBL11479365 | 0.69 | LMNA (0.34) | LMNASMN1; SMN2 | |
| SCHEMBL1992279 | 0.68 | MAPT (0.48) | NAMPTGRM5MAPK1PDK2 | |
| SCHEMBL10825318 | 0.67 | RAD52 (0.48) | LMNAALDH1A1MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | claimed |
| US-4223146-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1980-09-16 | — | — | US | disclosed |
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |