Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477158 | 0.89 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL11516079 | 0.74 | LMNA (0.45) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL10325665 | 0.74 | GRM5 (0.44) | GRM5PDK2NAMPT | |
| SCHEMBL11516242 | 0.73 | MEN1 (0.43) | LMNAALDH1A1MEN1KMT2AGRM5 | |
| Hydrochloric Acid SCHEMBL11516834 | 0.73 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8316966 | 0.69 | MAOA (0.36) | GRM5HRH3 | |
| SCHEMBL11491448 | 0.69 | DPP4 (0.35) | LMNA | |
| SCHEMBL1996747 | 0.68 | ESR2 (0.46) | GRM5MAPK1PDK2 | |
| SCHEMBL11479365 | 0.66 | LMNA (0.34) | LMNA | |
| SCHEMBL438780 | 0.64 | GRM5 (0.33) | GRM5PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223146-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1980-09-16 | — | — | US | claimed |
| US-4223146-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1980-09-16 | — | — | US | disclosed |