Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11516834 | 0.99 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11515901 | 0.86 | MEN1 (0.43) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11515869 | 0.85 | HRH3 (0.39) | MAPK1TDP1SMN1; SMN2ATMHRH3 | |
| Hydrochloric Acid SCHEMBL11517181 | 0.84 | HRH3 (0.39) | MAPK1TDP1SMN1; SMN2ATMHRH3 | |
| SCHEMBL11514216 | 0.80 | ALDH1A1 (0.39) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11517624 | 0.80 | ALDH1A1 (0.51) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11518328 | 0.80 | MAPT (0.45) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11515001 | 0.79 | ALDH1A1 (0.53) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11514380 | 0.77 | KMT2A (0.48) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11518462 | 0.76 | MAPT (0.43) | LMNAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | claimed |
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |