Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482479 | 0.74 | GPR35 (0.57) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL6956209 | 0.73 | HPGD (0.55) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11348725 | 0.73 | GPR35 (0.78) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL6962937 | 0.72 | HPGD (0.44) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11478258 | 0.72 | GPR35 (0.76) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11478244 | 0.71 | GPR35 (0.78) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL6957551 | 0.69 | HPGD (0.43) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11478579 | 0.69 | GPR35 (0.59) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL6961672 | 0.69 | ALDH1A1 (0.58) | LMNATDP1MEN1KMT2AAR | |
| Cromitrile Sodium SCHEMBL1649767 | 0.69 | GPR35 (0.46) | GPR35LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238495-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | disclosed |