Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11490261 | 0.88 | SMN1; SMN2 (0.44) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| SCHEMBL11479513 | 0.84 | HTR2A (0.53) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| Bromide SCHEMBL11245480 | 0.83 | HTR2A (0.52) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| Bromide SCHEMBL11318175 | 0.83 | HTR2A (0.54) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| SCHEMBL11315886 | 0.82 | HTR2A (0.54) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| SCHEMBL11255836 | 0.81 | DRD2 (0.45) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| Bromide SCHEMBL11482097 | 0.81 | HTR2A (0.53) | HRH1HTR2ADRD2SIGMAR1HTR1A | |
| SCHEMBL11248897 | 0.81 | HRH1 (0.56) | HRH1HTR2ADRD2HTR1ADRD3 | |
| Bromide SCHEMBL11473841 | 0.80 | HRH1 (0.56) | HRH1HTR2ADRD2HTR1ADRD3 | |
| SCHEMBL11490180 | 0.79 | HTR2A (0.54) | HRH1HTR2ADRD2SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198418-A | ANALGESICS, TRANQUILIZERS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |