Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248404 | 0.80 | SMN1; SMN2 (0.43) | KDM4EMAPTLMNAOPRM1SLC22A1 | |
| SCHEMBL11500046 | 0.79 | KDM4E (0.43) | KDM4EMAPTNPSR1LMNAHDAC4 | |
| SCHEMBL11258115 | 0.77 | RHEB (0.44) | KDM4EMAPTNPSR1LMNAOPRM1 | |
| SCHEMBL11483187 | 0.74 | SMN1; SMN2 (0.46) | KDM4EMAPTLMNAOPRM1SLC22A1 | |
| SCHEMBL4555610 | 0.73 | HDAC4 (0.62) | LMNAHDAC4ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5729723 | 0.72 | OPRM1 (0.48) | MAPTHDAC4OPRM1SLC22A1SLC6A4 | |
| Oxalic Acid SCHEMBL11487121 | 0.72 | KDM4E (0.50) | KDM4EMAPTLMNAOPRM1SLC22A1 | |
| SCHEMBL19469572 | 0.72 | HDAC4 (0.65) | LMNAHDAC4KMT2AGAATDP1 | |
| SCHEMBL11482078 | 0.71 | SMN1; SMN2 (0.44) | KDM4EMAPTLMNAOPRM1SLC22A1 | |
| SCHEMBL11477977 | 0.71 | SMN1; SMN2 (0.46) | KDM4EMAPTLMNAOPRM1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |