Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 8/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063291 | 1.00 | TP53 (0.49) | TP53TSHRRARBPLA2G4BALDH1A1 | |
| SCHEMBL11558611 | 1.00 | TP53 (0.49) | TP53TSHRRARBPLA2G4BALDH1A1 | |
| SCHEMBL8650224 | 0.98 | MLYCD (0.48) | TP53TSHRRARBPLA2G4BALDH1A1 | |
| SCHEMBL31572052 | 0.87 | ALDH1A1 (0.52) | TP53TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL11562403 | 0.86 | MLYCD (0.43) | TP53TSHRALDH1A1MAPTMLYCD | |
| SCHEMBL11559974 | 0.85 | NPC1 (0.51) | ALDH1A1MEN1MAPTKMT2AMLYCD | |
| Hydrochloric Acid SCHEMBL11559328 | 0.85 | MLYCD (0.45) | TP53TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1417508 | 0.85 | ALDH1A1 (0.56) | TP53TSHRALDH1A1MEN1MAPT | |
| SCHEMBL11513573 | 0.85 | ALDH1A1 (0.56) | TP53TSHRALDH1A1MEN1MAPT | |
| SCHEMBL11520102 | 0.85 | ALDH1A1 (0.56) | TP53TSHRALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198522-A | HYPOLIPIDEMIC ACND ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-15 | — | — | US | disclosed |