Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649102 | 0.99 | NPC1 (0.52) | NPC1CASP1RAB9AMGLLSTAT3 | |
| SCHEMBL21917833 | 0.88 | STAT3 (0.54) | NPC1CASP1RAB9ASTAT3HPGD | |
| SCHEMBL11309272 | 0.86 | HSD17B10 (0.50) | NPC1CASP1RAB9AMGLLMLYCD | |
| SCHEMBL11558611 | 0.85 | TP53 (0.49) | CASP1MEN1KMT2AMLYCDMAPT | |
| SCHEMBL9063291 | 0.85 | TP53 (0.49) | CASP1MEN1KMT2AMLYCDMAPT | |
| SCHEMBL11477348 | 0.85 | TP53 (0.49) | CASP1MEN1KMT2AMLYCDMAPT | |
| SCHEMBL11386176 | 0.84 | ALDH1A1 (0.45) | NPC1RAB9AHPGDMLYCDMAPT | |
| SCHEMBL8650224 | 0.84 | MLYCD (0.48) | CASP1MEN1KMT2AMLYCDMAPT | |
| Hydrochloric Acid SCHEMBL11559328 | 0.83 | MLYCD (0.45) | CASP1MEN1KMT2AMLYCDALDH1A1 | |
| SCHEMBL11562653 | 0.83 | HSD17B3 (0.43) | RAB9AMEN1KMT2AMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154756-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |