Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477217 | 0.91 | DRD2 (0.46) | FPR1FPR2DRD2GAASMN1; SMN2 | |
| SCHEMBL11478891 | 0.85 | DRD2 (0.52) | DRD2HRH3CHRNB4CHRNA3KDM2B | |
| SCHEMBL7749615 | 0.82 | CYP3A4 (0.38) | CHRM3 | |
| SCHEMBL11488360 | 0.82 | FPR1 (0.45) | FPR1FPR2DRD2CHRNB2 | |
| SCHEMBL6659010 | 0.82 | CYP3A4 (0.38) | CHRM3 | |
| SCHEMBL11478746 | 0.82 | CHRNB4 (0.46) | CHRNB4CHRNA3SMN1; SMN2KDM2B | |
| Hydrochloric Acid SCHEMBL11491667 | 0.81 | KDM4E (0.38) | CHRM3GAAKDM4E | |
| SCHEMBL11480023 | 0.80 | CHRNB4 (0.42) | CHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL29017331 | 0.78 | SIGMAR1 (0.52) | SPHK2 | |
| SCHEMBL11769008 | 0.78 | HRH3 (0.46) | HRH3SPHK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219560-A | ANTILIPEMIC AGENTS | SANDOZ, INC. (US) | 1980-08-26 | — | — | US | disclosed |