SCHEMBL709483

SCHEMBL709483

NNC(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.60
GRM6 O15303 1/20 0.60
GRIN2D O15399 1/20 0.60
GRIN3B O60391 1/20 0.60
GSR P00390 1/20 0.60
CYP1A2 P05177 1/20 0.60
GRIK1 P39086 1/20 0.60
GRM5 P41594 1/20 0.60
GRIA1 P42261 1/20 0.60
GRIA2 P42262 1/20 0.60
GRIA3 P42263 1/20 0.60
SLC1A3 P43003 1/20 0.60
SLC1A2 P43004 1/20 0.60
SLC1A1 P43005 1/20 0.60
GRIA4 P48058 1/20 0.60
GRIN1 Q05586 1/20 0.60
GRIN2A Q12879 1/20 0.60
GRIK2 Q13002 1/20 0.60
GRIK3 Q13003 1/20 0.60
GRIN2B Q13224 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709482 1.00 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
Thioacetamide SCHEMBL711295 0.89 DPP4 (0.50) GRM8GRM6GRIN2DGRIN3BGSR
Thioacetamide SCHEMBL711294 0.89 DPP4 (0.50) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29833669 0.82 BLM (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL1534035 0.82 CTSD (0.44) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL27741548 0.82 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL564272 0.82 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL1534041 0.82 CTSD (0.44) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL288407 0.82 BLM (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL11478144 0.82 BLM (0.58) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023124537-A1 CONJUGATE AND ANTIBODY-DRUG CONJUGATE PREPARED USING SAME 辽宁键凯科技有限公司 2023-07-06 WO claimed
US-8318503-B2 Method for determining the amount of conjugated taxane in polyglut acid-taxane conjugates CELL THERAPEUTICS, INC. (US) 2012-11-27 US claimed
EP-1967854-B1 Method for determining the amount of conjugated taxane in polyglutamic acid-taxane conjugates CELL THERAPEUTICS EUROPE SRL (IT) 2010-11-03 EP claimed
US-20100151582-A1 METHOD FOR DETERMINING THE AMOUNT OF CONJUGATED TAXANE IN POLYGLUT ACID-TAXANE CONJUGATES CELL THERAPEUTICS, INC. (US) 2010-06-17 US claimed
WO-2008107174-A1 METHOD FOR DETERMINING THE AMOUNT OF CONJUGATED TAXANE IN POLYGLUT ACID-TAXANE CONJUGATES CELL THERAPEUTICS INC. (US) 2008-09-12 WO claimed
EP-1967854-A1 Method for determining the amount of conjugated taxane in polyglutamic acid-taxane conjugates Cell Therapeutics Europe S.R.L. (IT) 2008-09-10 EP claimed
US-5079155-A Bioaffinity chromatography E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-07 US claimed
EP-0140556-A1 A T-DNA derived vector LUBRIZOL GENETICS INC. (US) 1985-05-08 EP claimed
EP-4593882-A1 MICROPARTICLE FORMULATIONS FOR INTRAVENOUS THERAPY AND METHODS FOR THEIR MANUFACTURE AND USE The Methodist Hospital (US) 2025-08-06 EP disclosed
US-12331197-B2 Power transmission belt DAYCO EUROPE S.R.L. (IT) 2025-06-17 US disclosed
EP-3404056-B1 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMER COMPOSITION ZEON CORP (JP) 2025-06-11 EP disclosed
CN-120076831-A Anti-ROR 1 antibodies and antibody conjugates, compositions comprising anti-ROR 1 antibodies or antibody conjugates, and methods of making and using anti-ROR 1 antibodies and antibody conjugates 苏特罗生物制药公司 2025-05-30 CN disclosed
CN-119455004-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-119455003-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-1052144-A The Compounds and methods for of diagnosis and treatment cancer AUSTRALIAN COMMERCIAL RESEARCH (AU) 1991-06-12 CN disclosed
US-4950738-A ANTICARCINOGENS CYTOGEN CORPORATION (US) 1990-08-21 US disclosed
WO-1988009823-A1 AMINE DERIVATIVES OF ANTHRACYCLINE ANTIBIOTICS AND ANTIBODY CONJUGATES THEREOF CYTOGEN CORPORATION (US) 1988-12-15 WO disclosed
EP-0294294-A2 Amine derivatives of anthracycline antibiotics CYTOGEN CORPORATION (US) 1988-12-07 EP disclosed
US-4745161-A Soluble and biodegradable polyamino acid activated for bonding of biologically active compound CESKOSLOVENSKA AKADEMIE VED (CS) 1988-05-17 US disclosed
EP-0140556-A1 A T-DNA derived vector LUBRIZOL GENETICS INC. (US) 1985-05-08 EP disclosed