Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478532 | 0.87 | MEN1 (0.55) | HIF1AMEN1KMT2AABCB1ALDH1A1 | |
| SCHEMBL1099465 | 0.79 | FABP1 (0.50) | PRMT5WDR77LMNA | |
| SCHEMBL28343012 | 0.78 | TSHR (0.64) | HIF1APRMT5WDR77MEN1KMT2A | |
| SCHEMBL773183 | 0.77 | PRMT5 (0.54) | HIF1APRMT5WDR77KMT2ATSHR | |
| SCHEMBL11480301 | 0.77 | ADRB2 (0.56) | MEN1KMT2AABCB1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11491938 | 0.77 | PRMT5 (0.49) | HIF1APRMT5WDR77TSHRPOLB | |
| SCHEMBL14546242 | 0.73 | KDM1A (0.55) | HIF1APRMT5WDR77MEN1KMT2A | |
| SCHEMBL258823 | 0.73 | HIF1A (0.75) | HIF1AABCB1ALDH1A1POLBLMNA | |
| SCHEMBL14173798 | 0.72 | MAPK1 (0.52) | HIF1APRMT5WDR77TSHRALDH1A1 | |
| SCHEMBL11745913 | 0.71 | NR2E1 (0.64) | MEN1KMT2AABCB1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241088-A | 1-(Trialkylamino)-3-(phenylphenoxy)-2-propanol quarternary salts | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1980-12-23 | — | — | US | disclosed |