Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478532 | 0.80 | MEN1 (0.55) | ADRB2ADRB1ALDH1A1CYP2D6MAPT | |
| SCHEMBL10203033 | 0.80 | ADRB2 (0.62) | ADRB2ADRB1HTR7ALDH1A1CYP2D6 | |
| SCHEMBL15677631 | 0.79 | ADRB2 (0.65) | ADRB2ADRB1HTR7ALDH1A1CYP2D6 | |
| SCHEMBL12473595 | 0.79 | ADRB2 (0.61) | ADRB2ADRB1HTR7ALDH1A1CYP2D6 | |
| SCHEMBL10408230 | 0.79 | ADRB2 (0.64) | ADRB2ADRB1HTR7ALDH1A1CYP2D6 | |
| SCHEMBL15094850 | 0.78 | ADRB2 (0.55) | ADRB2ADRB1HTR7ALDH1A1MAPT | |
| SCHEMBL11745913 | 0.78 | NR2E1 (0.64) | ADRB2ADRB1ALDH1A1CYP2D6ADRA1A | |
| SCHEMBL27838229 | 0.77 | ADRB2 (0.59) | ADRB2ADRB1HTR7ALDH1A1CYP2D6 | |
| SCHEMBL8226025 | 0.77 | HTR1A (0.51) | ADRB2ADRB1CYP2D6CYP1A2ABCB1 | |
| SCHEMBL11478733 | 0.77 | HIF1A (0.57) | ADRB2ADRB1ALDH1A1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241088-A | 1-(Trialkylamino)-3-(phenylphenoxy)-2-propanol quarternary salts | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1980-12-23 | — | — | US | disclosed |