Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252103 | 0.89 | KCNH2 (0.38) | KCNH2ALDH1A1LMNA | |
| SCHEMBL1147704 | 0.88 | TRPV1 (0.43) | TRPV1KCNH2 | |
| SCHEMBL1147907 | 0.88 | TRPV1 (0.43) | TRPV1KCNH2 | |
| SCHEMBL1147455 | 0.86 | KCNH2 (0.47) | TRPV1KCNH2 | |
| SCHEMBL1148023 | 0.84 | TRPV1 (0.45) | TRPV1KCNH2ALDH1A1LMNA | |
| SCHEMBL1147955 | 0.83 | TRPV1 (0.43) | TRPV1KCNH2 | |
| SCHEMBL1147957 | 0.81 | TRPV1 (0.41) | TRPV1KCNH2ALDH1A1LMNA | |
| SCHEMBL1147478 | 0.80 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3244059 | 0.79 | KCNH2 (0.40) | KCNH2ALDH1A1LMNA | |
| SCHEMBL1147672 | 0.78 | TRPV1 (0.48) | TRPV1KCNH2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888359-B2 | Cyclohexyl or piperidinyl carboxamide antibiotic derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-02-15 | — | — | US | claimed |
| US-7888359-B2 | Cyclohexyl or piperidinyl carboxamide antibiotic derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-02-15 | — | — | US | disclosed |
| EP-2001478-A1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107965-A1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-09-27 | — | — | WO | disclosed |