Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478385 | 0.84 | SMN1; SMN2 (0.50) | POLBLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7381407 | 0.83 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2ALDH1A1KDM4EGLA | |
| SCHEMBL811946 | 0.72 | BRD4 (0.37) | POLBSMN1; SMN2ALDH1A1KDM4EGLA | |
| SCHEMBL11480111 | 0.68 | MAOB (0.68) | LMNAALDH1A1KDM4EMEN1RAB9A | |
| SCHEMBL2202541 | 0.63 | SERPINE1 (0.42) | SMN1; SMN2ALDH1A1BCL9CTNNB1KDM4E | |
| SCHEMBL7357932 | 0.63 | NQO1 (0.64) | POLBLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28180641 | 0.63 | KDM4E (0.38) | POLBLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7354114 | 0.62 | NQO1 (0.63) | POLBSMN1; SMN2KDM4EGLAGAA | |
| SCHEMBL7350101 | 0.62 | NQO1 (0.63) | POLBSMN1; SMN2KDM4EGLAGAA | |
| SCHEMBL7357238 | 0.62 | NQO1 (0.63) | POLBSMN1; SMN2KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |