SCHEMBL2202541

SCHEMBL2202541

O=c1c(O)c(-c2ccc(F)cc2)c1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.42
ERCC1 P07992 2/20 0.41
ERCC4 Q92889 2/20 0.41
BCL9 O00512 1/20 0.41
CTNNB1 P35222 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
BCL2L1 Q07817 1/20 0.40
BAD Q92934 1/20 0.40
TYMP P19971 1/20 0.40
ABCB1 P08183 1/20 0.39
ACHE P22303 1/20 0.37
BACE1 P56817 1/20 0.37
MAPK14 Q16539 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13290009 0.98 SERPINE1 (0.41) SERPINE1ERCC1ERCC4BCL9CTNNB1
SCHEMBL9766788 0.78 MAPT (0.52) ERCC1ERCC4ESR1ESR2BCL2L1
SCHEMBL1109016 0.77 CYP3A4 (0.43) ACHEKDM4EALDH1A1GAARAB9A
SCHEMBL12432628 0.77 ALOX12 (0.42) BCL9CTNNB1ACHEALDH1A1HPGD
SCHEMBL2203880 0.76 MAPT (0.59) SERPINE1BCL2L1ABCB1KDM4EGAA
SCHEMBL13290007 0.75 ESR2 (0.50) ESR2MAPTCES2CES1
SCHEMBL12432447 0.74 MAPT (0.56) SERPINE1BCL2L1ABCB1KDM4EGAA
SCHEMBL13290010 0.74 ESR2 (0.48) ESR2MAPTCES2CES1
SCHEMBL8901808 0.73 TYMP (0.48) BCL2L1BADTYMPMAPK14KDM4E
SCHEMBL3671202 0.72 HDAC4 (0.56) ESR2BACE1KDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977393-B2 Composition containing oxocarbon and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-12 US disclosed
US-7977393-B2 Composition containing oxocarbon and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-12 US disclosed
US-7977393-B2 Composition containing oxocarbon and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-12 US disclosed
US-20100136459-A1 ELECTROLYTE CONTAINING OXOCARBON MOLECULE AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100136459-A1 ELECTROLYTE CONTAINING OXOCARBON MOLECULE AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20080160417-A1 Proton conductive membrane polymer electrolyte in a solid polymer type fuel cell using gas fuels, hydrogen gas, liquid fuels, methanol, dimethyl ether; flexibility without lowering proton conductivity; SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-03 US disclosed
US-20080160417-A1 Proton conductive membrane polymer electrolyte in a solid polymer type fuel cell using gas fuels, hydrogen gas, liquid fuels, methanol, dimethyl ether; flexibility without lowering proton conductivity; SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-03 US disclosed
US-20080160417-A1 Proton conductive membrane polymer electrolyte in a solid polymer type fuel cell using gas fuels, hydrogen gas, liquid fuels, methanol, dimethyl ether; flexibility without lowering proton conductivity; SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-03 US disclosed
EP-1845135-A1 COMPOSITION CONTAINING OXOCARBON AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-10-17 EP disclosed
EP-1845135-A1 COMPOSITION CONTAINING OXOCARBON AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100136459-A1 ELECTROLYTE CONTAINING OXOCARBON MOLECULE AND USE THEREOF EPCAM, CCNE2, ESR1 SERPINE1 4853/4885ERCC1 264/4885ERCC4 951/4885
US-20080160417-A1 Proton conductive membrane polymer electrolyte in a solid polymer type fuel cell using gas fuels, hydrogen gas, liquid fuels, methanol, dimethyl ether; flexibility without lowering proton conductivity; HVCN1, MPC2, SLC9A1 SERPINE1 4515/4885ERCC1 315/4885ERCC4 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.