Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480482 | 0.72 | POLB (0.39) | GAAKMT2ACYP1A2CYP2C19POLB | |
| SCHEMBL11478385 | 0.71 | SMN1; SMN2 (0.50) | GAAMAPTCYP1A2CYP2C19POLB | |
| SCHEMBL8476247 | 0.70 | CSNK2A2 (0.46) | GAATP53MAPTCSNK2A2CSNK2B | |
| SCHEMBL7219386 | 0.70 | MAPT (0.46) | GAATP53MAPTCSNK2A2CSNK2B | |
| SCHEMBL7381407 | 0.70 | SMN1; SMN2 (0.49) | GAAMAPTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL812046 | 0.69 | NPC1 (0.41) | GAAKMT2ACYP1A2CYP2C19POLB | |
| SCHEMBL812011 | 0.63 | ACACB (0.38) | BRD4TP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL812007 | 0.62 | PGR (0.40) | GAATP53MAPTCSNK2A2CSNK2B | |
| SCHEMBL812271 | 0.62 | ACACB (0.37) | BRD4ALDH1A1HSD17B10USP2 | |
| SCHEMBL812275 | 0.62 | ALDH1A1 (0.47) | TP53MAPTKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | KCNE1, DDT, KCNQ3 | BRD4 2425/4885GAA 1025/4885TP53 3088/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | BRD4 2425/4885GAA 1025/4885TP53 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.