SCHEMBL11480751

SCHEMBL11480751

O=[C]Cc1ccccc1C[C]=O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.36
GABRB2 P47870 3/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TAAR1 Q96RJ0 6/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP1B1 Q16678 1/20 0.35
DPP4 P27487 1/20 0.33
HSPA5 P11021 1/20 0.33
LMNA P02545 1/20 0.33
AKR1B1 P15121 1/20 0.33
KMT2A Q03164 1/20 0.32
IDO1 P14902 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96154 0.89 GABRA1 (0.45) GABRA1GABRB2ALDH1A1TAAR1L3MBTL1
SCHEMBL7687789 0.87 APOBEC3G (0.43) ALDH1A1HPGDTAAR1DPP4LMNA
SCHEMBL6875423 0.87 DPP4 (0.46) TAAR1DPP4
SCHEMBL2139391 0.84 TAAR1 (0.50) ALDH1A1TAAR1CYP1A2LMNAKMT2A
SCHEMBL910032 0.83 DAO (0.38) GABRA1GABRB2TAAR1
SCHEMBL9317847 0.82 FFAR1 (0.31) GABRA1GABRB2ALDH1A1HPGD
SCHEMBL96464 0.82 TAAR1 (0.52) TAAR1CYP1A2LMNAIDO1
SCHEMBL811980 0.82 TAAR1 (0.52) ALDH1A1HPGDTAAR1LMNAKMT2A
SCHEMBL360936 0.82 FDPS (0.41) ALDH1A1HPGDTAAR1LMNAL3MBTL1
SCHEMBL97462 0.82 TAAR1 (0.52) GABRA1GABRB2ALDH1A1HPGDTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4202816-A ENOL-PIPERIDINE METAL COMPLEXES CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed