SCHEMBL9317847

SCHEMBL9317847

O=[C]Cc1ccccc1[C]=O

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.31
FFAR4 Q5NUL3 2/20 0.31
TSPO P30536 1/20 0.31
DRD3 P35462 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4797057 0.82 CYP19A1 (0.43) FFAR1ALDH1A1
SCHEMBL11480751 0.82 GABRA1 (0.36) ALDH1A1HPGDGABRA1GABRB2
SCHEMBL535892 0.78 GABRA1 (0.45) FFAR1ALDH1A1GABRA1GABRB2
SCHEMBL9036603 0.77 TAAR1 (0.50)
SCHEMBL873220 0.76 FFAR1 (0.44) FFAR1ALDH1A1HPGD
SCHEMBL1379506 0.76 ALDH1A1 (0.42) ALDH1A1GABRA1GABRB2
SCHEMBL1465518 0.76 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL3021179 0.76 TRPA1 (0.35) ALDH1A1GABRA1GABRB2
SCHEMBL3644028 0.76 PNMT (0.44) GABRA1GABRB2
SCHEMBL2139391 0.73 TAAR1 (0.50) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6087810-A None JP disclosed
JP-H0687810-A 4-@(3754/24)AMINOMETHYL)CYCLOHEXANECARBOXAMIDE DERIVATIVE SUNTORY LTD 1994-03-29 JP disclosed