Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148152 | 0.83 | NPSR1 (0.45) | NPSR1HPGDGAAMEN1KMT2A | |
| SCHEMBL11718996 | 0.70 | LMNA (0.52) | NPSR1HPGDGAAPOLBMEN1 | |
| SCHEMBL22604385 | 0.70 | GAA (0.60) | GAAACACBMEN1KMT2AALDH1A1 | |
| SCHEMBL17465463 | 0.69 | ALDH1A1 (0.49) | NPSR1GAAPOLBMEN1KMT2A | |
| SCHEMBL16173575 | 0.68 | ITGB3 (0.58) | GAAACACBPOLBMEN1KMT2A | |
| SCHEMBL11887264 | 0.68 | PARP10 (0.58) | NPSR1HPGDGAAKMT2AALDH1A1 | |
| SCHEMBL11711239 | 0.68 | NPSR1 (0.55) | NPSR1HPGDPOLBMEN1KMT2A | |
| SCHEMBL11012644 | 0.68 | LMNA (0.70) | NPSR1HPGDGAAPOLBMEN1 | |
| SCHEMBL13613724 | 0.68 | CA14 (0.46) | GAAMEN1KMT2ALMNA | |
| SCHEMBL12281961 | 0.68 | CA14 (0.46) | GAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884103-B2 | such as N-(4-Chloro-phenyl)-2-methyl-2-phenylmethanesulfonylamino-3-(4-[1,2,4]triazol-1-yl-phenoxy)-propionamide, used for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-07-05 | — | — | US | disclosed |
| EP-1660441-A2 | N-SULFONYL-ALPHA-AMINO-ACID DERIVATIVES | Syngenta Participations AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021490-A2 | N-SULFONYL-α-AMINO-ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | C3AR1, GLRA1, C5AR1 | NPSR1 780/4885HPGD 3872/4885GAA 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.