Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478885 | 0.88 | CYP2C9 (0.59) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL8163677 | 0.86 | AGBL2 (0.56) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11475512 | 0.83 | MAPT (0.39) | CYP2C9CYP2C19HPGDSMN1; SMN2AGBL2 | |
| SCHEMBL11402424 | 0.80 | CYP2C9 (0.51) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL3765157 | 0.77 | HPGD (0.78) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11475823 | 0.76 | CAMK2A (0.47) | LMNACYP2D6CFDF11TPSB2 | |
| SCHEMBL11453265 | 0.74 | AGBL2 (0.50) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11407313 | 0.74 | AGBL2 (0.62) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11402193 | 0.74 | AGBL2 (0.76) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL7031188 | 0.74 | AGBL2 (0.42) | HPGDSMN1; SMN2AGBL2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205170-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-05-27 | — | — | US | disclosed |