Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163677 | 0.86 | AGBL2 (0.56) | AGBL2L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7037491 | 0.76 | AGBL2 (0.46) | AGBL2L3MBTL1KMT2AHPGD | |
| SCHEMBL11394789 | 0.75 | AGBL2 (0.52) | AGBL2L3MBTL1MAPTHPGD | |
| SCHEMBL9630038 | 0.74 | AGBL2 (0.46) | AGBL2L3MBTL1MEN1KMT2A | |
| SCHEMBL11481602 | 0.74 | CYP2C9 (0.50) | AGBL2SMN1; SMN2LMNATDP1HPGD | |
| SCHEMBL11478885 | 0.73 | CYP2C9 (0.59) | AGBL2SMN1; SMN2LMNATDP1HPGD | |
| SCHEMBL27405423 | 0.73 | ALDH1A1 (0.40) | L3MBTL1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL11403527 | 0.72 | AGBL2 (0.54) | AGBL2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28375579 | 0.72 | AGBL2 (0.56) | AGBL2L3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL11402193 | 0.72 | AGBL2 (0.76) | AGBL2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922704-B1 | PROCESS FOR PREPARING 2-(10,11-DIHYDRO-10-OXODIBENZO b,f]THIEPIN-2-YL)PROPIONIC ACID AND INTERMEDIATES THEREFOR | NIPPON CHEMIPHAR CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6111115-A | Preparation of 2-(10,11-dihydro-10-oxodibenzo-[b,f]thiepin-2-yl) propionic acid | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0922704-A1 | PROCESS FOR PREPARING 2-(10,11-DIHYDRO-10-OXODIBENZO b,f]THIEPIN-2-YL)PROPIONIC ACID AND INTERMEDIATES THEREFOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 1999-06-16 | — | — | EP | disclosed |