Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 4/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.55 |
| ▸ | MMP12 | P39900 | 4/20 | 0.55 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481602 | 0.88 | CYP2C9 (0.50) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL8163677 | 0.86 | AGBL2 (0.56) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11400370 | 0.83 | AKR1B1 (0.46) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11407313 | 0.83 | AGBL2 (0.62) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11453265 | 0.83 | AGBL2 (0.50) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11402193 | 0.83 | AGBL2 (0.76) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11402424 | 0.82 | CYP2C9 (0.51) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11398613 | 0.81 | MMP2 (0.44) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11403527 | 0.81 | AGBL2 (0.54) | CYP2C9CYP2C19HPGDMMP2MMP9 | |
| SCHEMBL11394902 | 0.81 | MMP2 (0.44) | CYP2C9CYP2C19HPGDMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205170-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-05-27 | — | — | US | disclosed |