Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481924 | 1.00 | TRPM8 (0.68) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| Hydrochloric Acid SCHEMBL27699758 | 0.98 | TRPM8 (0.67) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL17691541 | 0.89 | MAPT (0.71) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL16576815 | 0.88 | TRPM8 (0.68) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL27675421 | 0.84 | TRPM8 (0.56) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL11766659 | 0.84 | ALDH1A1 (0.60) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL11766665 | 0.84 | ALDH1A1 (0.60) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL24419889 | 0.84 | TRPM8 (0.50) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL9548237 | 0.84 | MAPT (0.60) | TRPM8ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL9548241 | 0.84 | MAPT (0.60) | TRPM8ALDH1A1KDM4EMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209517-A | α-Ethylenic alcohols and ketones, their preparation, and their use as medicaments | UNICLER (FR) | 1980-06-24 | — | — | US | disclosed |
| US-4012232-A | Stabilized photochromic materials | Chu, Nori Y. C. (US) | 1977-03-15 | — | — | US | disclosed |