Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17691541 | 0.92 | MAPT (0.71) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL11481924 | 0.88 | TRPM8 (0.68) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL11481925 | 0.88 | TRPM8 (0.68) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL11482626 | 0.86 | MAPT (0.59) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL11482623 | 0.86 | MAPT (0.59) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL9548241 | 0.86 | MAPT (0.60) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL9548237 | 0.86 | MAPT (0.60) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27699758 | 0.86 | TRPM8 (0.67) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL3218729 | 0.85 | MAPT (0.67) | TRPM8MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL3218704 | 0.85 | MAPT (0.67) | TRPM8MAPTAPPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895322-B2 | Pharmaceutical compositions for the delivery of substantially water-insoluble drugs | SINGH MEWA (US) | 2018-02-20 | — | — | US | disclosed |
| US-20150080353-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE DELIVERY OF SUBSTANTIALLY WATER-INSOLUBLE DRUGS | SINGH MEWA (US) | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080353-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE DELIVERY OF SUBSTANTIALLY WATER-INSOLUBLE DRUGS | PTGS2, PTGES2, ABCG2 | TRPM8 3793/4885MAPT 320/4885APP 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.