Toluene

Toluene

SCHEMBL1148280

Cc1ccccc1.O=S(=O)(O)Cl

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
TSHR P16473 2/20 0.58
ALOX12 P18054 2/20 0.58
ACHE P22303 2/20 0.58
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
HSD17B10 Q99714 1/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
RECQL P46063 1/20 0.41
HSD11B1 P28845 1/20 0.41
NOD2 Q9HC29 1/20 0.41
HTT P42858 2/20 0.41
GAA P10253 3/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27751750 0.97 LMNA (0.55) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL28202360 0.97 LMNA (0.55) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL28236662 0.97 LMNA (0.55) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL28184685 0.93 LMNA (0.50) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL11123126 0.89 LMNA (0.65) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL248686 0.89 LMNA (0.65) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL2874261 0.89 ALOX12 (0.65) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL53563 0.89 ALOX12 (0.65) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL14976964 0.89 ALOX12 (0.65) LMNATSHRALOX12ACHESMN1; SMN2
Toluene SCHEMBL28783164 0.89 ALOX12 (0.65) LMNATSHRALOX12ACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229179-A Preparation method and application of in-situ authigenic viscosity-reducing surfactant for oil displacement 东营宝莫环境工程有限公司 2023-12-15 CN claimed
CN-110452146-A Trifluoromethyl seleno-amino acids derivative and preparation method thereof UNIV WUHAN TECH 2019-11-15 CN claimed
CN-107383240-B A kind of amino chitin and its preparation method and application 中国科学院烟台海岸带研究所 2019-11-15 CN claimed
CN-110396059-A A kind of synthetic method of 5- cyanoindole SUZHOU HANDE CHUANGHONG BIOCHEMISTRY TECH CO LTD 2019-11-01 CN claimed
CN-110357870-A A kind of preparation method of fluorescent molecular probe for detecting formaldehyde and preparation method and its fluorescent test paper 中南大学 2019-10-22 CN claimed
CN-110283222-A A kind of pet imaging agent18F-FPGalNAc and its preparation method and application 南方医科大学南方医院 2019-09-27 CN claimed
CN-110237043-A It is a kind of to be sustained dripping pill matrix resistant to high temperature and the Lonicera and scutellaria drip pill comprising the matrix 浙江维康药业股份有限公司 2019-09-17 CN claimed
CN-107304221-B The purposes of tetraterpene derivatives and its anti-Ebola virus 北京大学 2019-09-13 CN claimed
CN-107075105-B Moisture-curable, polyether carbonic ester containing alkoxysilyl 科思创德国股份有限公司 2019-09-13 CN claimed
CN-110054558-A A kind of preparation method of 1- trifluoromethyl cyclopropane -1- formic acid 海门瑞一医药科技有限公司 2019-07-26 CN claimed
CN-104353439-A Preparation method and application of adsorbent UNIV ANHUI NORMAL 2015-02-18 CN claimed
CN-103269723-A Materials and methods for conjugating a water soluble fatty acid derivative to a protein BAXTER INT 2013-08-28 CN claimed
CN-102672799-A Manufacturing method of flow guide drum of single crystal furnace GANSU HAOSHI CARBON FIBER CO LTD 2012-09-19 CN claimed
CN-101605457-A P-toluenesulfonate of 5-amino-3-(2'-0-acetyl-3'-deoxy-beta-D-ribofuranosyl)-3H-thiazole [4,5-D] pyrimidin-2-one and method of preparation ANADYS PHARMACEUTICALS INC (US) 2009-12-16 CN claimed
CN-101605591-A Crosslinked cellulose membranes GE HEALTHCARE BIO SCIENCES AB (SE) 2009-12-16 CN claimed
CN-100374197-C Solid compositions for selective adsorption from complex mixtures GRACE W R & CO (US) 2008-03-12 CN claimed
CN-1777432-A Antiviral nucleoside analogs and methods for treating viral infections, particularly HIV infections UNIV YALE (US) 2006-05-24 CN claimed
CN-1568222-A Solid compositions for selective adsorption from complex mixtures GRACE W R & CO (US) 2005-01-19 CN claimed
EP-0272213-B1 PROCESS FOR THE OXIDATION OF AROMATIC SECONDARY ALCOHOLS CIBA-GEIGY AG (CH) 1991-07-10 EP claimed
EP-0272213-A2 Process for the oxidation of aromatic secondary alcohols CIBA-GEIGY AG (CH) 1988-06-22 EP claimed