Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6143462 | 0.84 | EPHX1 (0.54) | KMT2ASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL11218025 | 0.82 | SMN1; SMN2 (0.42) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27859979 | 0.79 | IDO1 (0.42) | SMN1; SMN2HPGDALDH1A1LMNAGAA | |
| SCHEMBL7396455 | 0.79 | RAB9A (0.43) | KMT2AL3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL28396949 | 0.78 | CYP2C19 (0.44) | KMT2AL3MBTL1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7844886 | 0.77 | SMN1; SMN2 (0.47) | KMT2AL3MBTL1SMN1; SMN2MAPTHPGD | |
| SCHEMBL3080810 | 0.77 | CYP2C19 (0.47) | KMT2AL3MBTL1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3063086 | 0.76 | IDO1 (0.43) | KMT2ASMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL3074971 | 0.76 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL1275763 | 0.75 | PKM (0.49) | KMT2AL3MBTL1SMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4203897-A | Penam derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |