SCHEMBL1148352

SCHEMBL1148352

CC(NC(=O)c1cc(Cl)cc(Br)c1NC(=O)C1CC(OS(=O)(=O)c2ccccc2[N+](=O)[O-])=NN1c1ncccc1Cl)C1CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32
MALT1 Q9UDY8 5/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
F2 P00734 2/20 0.31
ADAMTS5 Q9UNA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148277 0.93 MALT1 (0.35) IDO1MALT1L3MBTL1F2ADAMTS5
SCHEMBL1148544 0.91 GPR17 (0.33) IDO1MALT1
SCHEMBL1148359 0.90 F10 (0.35) IDO1MALT1L3MBTL1F2
SCHEMBL1148232 0.89 GPR17 (0.35) MALT1F2
SCHEMBL1148202 0.89 IDO1 (0.34) IDO1MALT1
SCHEMBL15085581 0.88 MALT1 (0.32) IDO1MALT1
SCHEMBL591565 0.88 MALT1 (0.36) IDO1MALT1
SCHEMBL591460 0.88 MALT1 (0.33) IDO1MALT1
SCHEMBL1148353 0.88 F10 (0.35) L3MBTL1F2
SCHEMBL1148386 0.87 MALT1 (0.33) IDO1MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 IDO1 288/4885MALT1 3967/4885L3MBTL1 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.