SCHEMBL1148232

SCHEMBL1148232

CC(NC(=O)c1cc(Cl)cc(Br)c1NC(=O)C1CC(OS(=O)(=O)c2cccc([N+](=O)[O-])c2)=NN1c1ncccc1Cl)C1CC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 10/20 0.35
P2RY2 P41231 5/20 0.35
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32
KDR P35968 1/20 0.32
F2 P00734 1/20 0.32
EPHX2 P34913 1/20 0.31
MALT1 Q9UDY8 1/20 0.31
ALDH1A1 P00352 2/20 0.31
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148544 0.94 GPR17 (0.33) GPR17P2RY2KMT2AMALT1ALDH1A1
SCHEMBL1148360 0.93 GPR17 (0.36) GPR17P2RY2MEN1KMT2AFLT1
SCHEMBL1147738 0.90 GPR17 (0.37) GPR17P2RY2MEN1KMT2AFLT1
SCHEMBL591460 0.89 MALT1 (0.33) MALT1
SCHEMBL1148352 0.89 IDO1 (0.32) F2MALT1
SCHEMBL1148374 0.89 TSHR (0.35) MALT1ALDH1A1
SCHEMBL1148386 0.89 MALT1 (0.33) MALT1
SCHEMBL1148230 0.88 GPR17 (0.34) GPR17P2RY2MEN1KMT2AFLT1
SCHEMBL1148301 0.88 MALT1 (0.35) GPR17P2RY2MEN1KMT2AEPHX2
SCHEMBL591565 0.87 MALT1 (0.36) MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 GPR17 4172/4885P2RY2 3126/4885MEN1 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.