SCHEMBL1148383

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14048064	0.89	HSP90AA1 (0.52)	MAPTALDH1A1KDM4EHSP90AA1LMNA
	SCHEMBL1147975	0.86	AKR1C3 (0.38)	MAPTMEN1ALDH1A1KMT2AMAPK1
	SCHEMBL5005998	0.83	MAPT (0.40)	MAPTMEN1ALDH1A1KMT2AKDM4E
	SCHEMBL1147978	0.83	ALDH1A1 (0.44)	MAPTMEN1ALDH1A1KMT2AKDM4E
	SCHEMBL4786773	0.82	HSP90AA1 (0.52)	MAPTMEN1ALDH1A1KMT2AKDM4E
	SCHEMBL1148602	0.81	APP (0.38)	MEN1ALDH1A1KMT2AKDM4EUSP2
	SCHEMBL1148698	0.81	HSP90AA1 (0.50)	MAPTMEN1ALDH1A1KMT2AKDM4E
	SCHEMBL13983495	0.80	HSP90AA1 (0.33)	MAPTMEN1ALDH1A1KMT2AKDM4E
	SCHEMBL15287894	0.80	HSP90AA1 (0.48)	HSP90AA1HSP90AB1
	SCHEMBL14456189	0.80	DRD2 (0.36)	MAPTMEN1ALDH1A1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.