SCHEMBL1148698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1148726	0.89	ALDH1A1 (0.42)	HSP90AA1HSP90AB1MEN1RAB9AKMT2A
	SCHEMBL1148637	0.89	HSP90AA1 (0.40)	HSP90AA1HSP90AB1MEN1RAB9AKMT2A
	SCHEMBL1148574	0.87	HSP90AA1 (0.38)	HSP90AA1HSP90AB1KDM4EMAPTALDH1A1
	SCHEMBL1147910	0.85	HSP90AA1 (0.36)	HSP90AA1HSP90AB1KDM4EMAPTGAA
	SCHEMBL13983495	0.83	HSP90AA1 (0.33)	HSP90AA1HSP90AB1MEN1KMT2AKDM4E
	SCHEMBL1147921	0.82	LMNA (0.36)	HSP90AA1HSP90AB1MEN1KMT2AMAPT
	SCHEMBL1148484	0.82	LMNA (0.36)	HSP90AA1HSP90AB1MEN1KMT2AMAPT
	SCHEMBL14218385	0.81	HSP90AA1 (0.34)	HSP90AA1HSP90AB1
	SCHEMBL4740712	0.81	HSP90AA1 (0.75)	HSP90AA1HSP90AB1G6PD
	SCHEMBL1148450	0.81	HSP90AA1 (0.32)	HSP90AA1HSP90AB1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.