Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370345 | 1.00 | TSHR (0.49) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL5696538 | 0.94 | LMNA (0.45) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL5696500 | 0.87 | LMNA (0.51) | TSHRTP53LMNACES2CES1 | |
| SCHEMBL1194007 | 0.84 | TSHR (0.51) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL7589520 | 0.84 | TSHR (0.51) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL9577653 | 0.83 | TSHR (0.54) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL11345805 | 0.83 | TSHR (0.50) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL83075 | 0.83 | TSHR (0.49) | TSHRTP53PLA2G4BLMNACES2 | |
| Water SCHEMBL28127794 | 0.81 | TSHR (0.47) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL9999772 | 0.81 | ALDH1A1 (0.53) | TSHRTP53PLA2G4BLMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204867-A | THIAZOLE OR IMIDAZOLE FOUR EQUILVALENT COUPLERS | AGFA-GEVAERT, A.G. (DE) | 1980-05-27 | — | — | US | disclosed |
| US-4183752-A | DEVELOPMENT INHIBITOR RELEASING THIOETHERS | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |