Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486549 | 1.00 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2LTB4RCA2 | |
| SCHEMBL11486383 | 0.98 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2LTB4RCA2 | |
| SCHEMBL11483225 | 0.93 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2HTR1AHTR7 | |
| SCHEMBL11490664 | 0.87 | SLC6A2 (0.46) | SLC6A4SLC6A3SLC6A2HTR1AHTR7 | |
| SCHEMBL11484616 | 0.83 | SLC6A3 (0.45) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL20615433 | 0.83 | SLC6A3 (0.47) | SLC6A4SLC6A3SLC6A2KCNH2CYP3A4 | |
| SCHEMBL11484268 | 0.83 | SLC6A3 (0.45) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| Lodelaben SCHEMBL636150 | 0.82 | LTB4R (0.46) | LTB4RPTGER2 | |
| SCHEMBL10897780 | 0.82 | LTB4R (0.46) | LTB4RPTGER2 | |
| SCHEMBL10606123 | 0.81 | SLC6A3 (0.44) | SLC6A4SLC6A3SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4185992-A | Imidazole derivatives | MAY & BAKER LIMITED (GB) | 1980-01-29 | — | — | US | disclosed |