Lodelaben

Lodelaben

SCHEMBL636150

CCCCCCCCCCCCCCCCCC(O)c1ccc(C(=O)O)c(Cl)c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 5/20 0.46
TSHR P16473 1/20 0.44
CASP1 P29466 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PPARA Q07869 2/20 0.43
ALDH1A1 P00352 1/20 0.43
MYC P01106 1/20 0.42
NR4A1 P22736 1/20 0.42
PTGER2 P43116 2/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
PPARG P37231 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
KAT8 Q9H7Z6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10897780 0.89 LTB4R (0.46) LTB4RPPARAALDH1A1PTGER2AKR1C2
SCHEMBL11486549 0.82 SLC6A4 (0.45) LTB4RPTGER2
SCHEMBL11484183 0.82 SLC6A4 (0.45) LTB4RPTGER2
SCHEMBL10727511 0.81 KAT8 (0.58) LTB4RPPARAALDH1A1ADRB1ADRB3
SCHEMBL11486383 0.80 SLC6A4 (0.45) LTB4RSMN1; SMN2ALDH1A1
SCHEMBL19374907 0.78 TSHR (0.47) TSHRCASP1SMN1; SMN2ALDH1A1MYC
SCHEMBL8012446 0.75 TP53 (0.54) TSHRALDH1A1PTGER2
SCHEMBL6472997 0.75 TP53 (0.54) TSHRALDH1A1PTGER2
SCHEMBL7770435 0.75 TP53 (0.54) TSHRALDH1A1PTGER2
SCHEMBL6473261 0.75 TP53 (0.54) TSHRALDH1A1PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-05-14 US claimed
US-20240216353-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-07-04 US claimed
US-20210315873-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2021-10-14 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-0126372-B1 HALOGENATED PROTEASE INHIBITORS G.D. Searle & Co. (US) 1986-07-16 EP claimed
EP-0126372-A1 Halogenated protease inhibitors G.D. Searle & Co. (US) 1984-11-28 EP claimed
US-4469885-A Halogenated protease inhibitors G. D. SEARLE & CO. (US) 1984-09-04 US claimed
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-05-14 US disclosed
EP-0126372-A1 Halogenated protease inhibitors G.D. Searle & Co. (US) 1984-11-28 EP disclosed
US-4469885-A Halogenated protease inhibitors G. D. SEARLE & CO. (US) 1984-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION SERPINB1, ELANE, CELA1 LTB4R 395/4885TSHR 3192/4885CASP1 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.