SCHEMBL11484697

SCHEMBL11484697

CC1(C)CC2(CC(C)(C)N1Cc1ccccc1)C(=O)N(c1ccccc1)C(=S)N2Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.42
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
AMPD2 Q01433 1/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11479811 0.77 ELANE (0.49) ELANEMEN1KMT2AAMPD2GAA
SCHEMBL16769259 0.77 ELANE (0.43) ELANEAMPD2GAAALDH1A1
SCHEMBL10124658 0.75 ELANE (0.41) ELANEAMPD2
SCHEMBL18697248 0.73 MCHR1 (0.41) ELANE
SCHEMBL10124656 0.73 ELANE (0.41) ELANEAMPD2
SCHEMBL10124664 0.71 ELANE (0.40) ELANEALDH1A1
SCHEMBL11479428 0.70 ELANE (0.43) ELANEMEN1KMT2AAMPD2ALDH1A1
SCHEMBL10124665 0.70 ELANE (0.36) ELANEMEN1KMT2AALDH1A1
SCHEMBL11479019 0.69 ELANE (0.49) ELANEMEN1KMT2AGAAALDH1A1
SCHEMBL11483953 0.69 POLB (0.50) ELANEMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US disclosed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US disclosed
US-3941744-A SYNTHETIC RESIN SANKYO COMPANY LIMITED (JA) 1976-03-02 US disclosed