SCHEMBL10124665

SCHEMBL10124665

CC1(C)CC2(CC(C)(C)N1OC1CCCCC1)C(=O)N(c1ccccc1)C(=O)N2Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.36
MCHR1 Q99705 4/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GCGR P47871 1/20 0.34
BACE1 P56817 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TAS2R8 Q9NYW2 1/20 0.34
IGF1R P08069 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124658 0.85 ELANE (0.41) ELANEMCHR1TAS2R8
SCHEMBL18697248 0.83 MCHR1 (0.41) ELANEMCHR1TAS2R8
SCHEMBL10124656 0.83 ELANE (0.41) ELANEMCHR1GCGRTAS2R8
SCHEMBL10124664 0.81 ELANE (0.40) ELANEMCHR1GCGRALDH1A1TAS2R8
SCHEMBL16769259 0.80 ELANE (0.43) ELANEMCHR1ALDH1A1TAS2R8
SCHEMBL10124667 0.78 ELANE (0.38) ELANEMCHR1GCGRMEN1KMT2A
SCHEMBL10124668 0.78 ELANE (0.38) ELANEMCHR1GCGRMEN1KMT2A
SCHEMBL10124654 0.76 POLB (0.42) ELANEMEN1KMT2AALDH1A1
SCHEMBL10124678 0.75 CACNA1B (0.35) ELANEMEN1KMT2AALDH1A1
SCHEMBL10124696 0.70 MT-CO2 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
WO-2010142576-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885MCHR1 780/4885L3MBTL1 994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.