SCHEMBL10124656

SCHEMBL10124656

CCON1C(C)(C)CC2(CC1(C)C)C(=O)N(c1ccccc1)C(=O)N2Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.41
NPSR1 Q6W5P4 1/20 0.39
MCHR1 Q99705 4/20 0.37
TAS2R8 Q9NYW2 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
GCGR P47871 1/20 0.35
AMPD2 Q01433 1/20 0.34
AR P10275 1/20 0.34
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124664 0.91 ELANE (0.40) ELANENPSR1MCHR1TAS2R8CYP1A2
SCHEMBL10124658 0.88 ELANE (0.41) ELANENPSR1MCHR1TAS2R8AMPD2
SCHEMBL10124668 0.87 ELANE (0.38) ELANENPSR1MCHR1TAS2R8CYP1A2
SCHEMBL10124667 0.87 ELANE (0.38) ELANENPSR1MCHR1TAS2R8CYP1A2
SCHEMBL18697248 0.86 MCHR1 (0.41) ELANENPSR1MCHR1TAS2R8HTR1A
SCHEMBL16769259 0.83 ELANE (0.43) ELANENPSR1MCHR1TAS2R8AMPD2
SCHEMBL10124665 0.83 ELANE (0.36) ELANEMCHR1TAS2R8GCGR
SCHEMBL10124648 0.73 ELANE (0.41) ELANEAR
SCHEMBL11484697 0.73 ELANE (0.42) ELANEAMPD2
SCHEMBL10124677 0.71 ELANE (0.39) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
WO-2010142576-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885NPSR1 48/4885MCHR1 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.