SCHEMBL18697248

SCHEMBL18697248

CC1(C)CC2(CC(C)(C)N1Oc1ccccc1)C(=O)N(c1ccccc1)C(=O)N2Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 10/20 0.41
ELANE P08246 4/20 0.39
CYP3A4 P08684 3/20 0.37
NPSR1 Q6W5P4 1/20 0.36
TAS2R8 Q9NYW2 1/20 0.36
HTR1A P08908 1/20 0.36
HTR7 P34969 1/20 0.36
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124658 0.88 ELANE (0.41) MCHR1ELANECYP3A4NPSR1TAS2R8
SCHEMBL10124656 0.86 ELANE (0.41) MCHR1ELANENPSR1TAS2R8HTR1A
SCHEMBL10124664 0.84 ELANE (0.40) MCHR1ELANENPSR1TAS2R8
SCHEMBL16769259 0.83 ELANE (0.43) MCHR1ELANENPSR1TAS2R8HTR1A
SCHEMBL10124665 0.83 ELANE (0.36) MCHR1ELANETAS2R8
SCHEMBL10124667 0.81 ELANE (0.38) MCHR1ELANENPSR1TAS2R8HTR1A
SCHEMBL10124668 0.81 ELANE (0.38) MCHR1ELANENPSR1TAS2R8HTR1A
SCHEMBL11484697 0.73 ELANE (0.42) ELANE
SCHEMBL18697263 0.72 POLB (0.40) ELANE
SCHEMBL18697264 0.70 ELANE (0.35) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed