Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361940 | 1.00 | ADORA2A (0.50) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL11484639 | 0.99 | KDM4E (0.49) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL1162642 | 0.91 | ADORA2A (0.42) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL11486783 | 0.88 | MAPT (0.50) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL11354056 | 0.87 | KDM4E (0.54) | ADORA2AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11491085 | 0.87 | KDM4E (0.46) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL11464145 | 0.87 | MEN1 (0.46) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL11490087 | 0.87 | MET (0.52) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL11485030 | 0.87 | KDM4E (0.48) | ADORA2AHPGDKDM4EALDH1A1RXFP1 | |
| SCHEMBL11490910 | 0.85 | L3MBTL1 (0.40) | ADORA2AHPGDKDM4EALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182887-A | ANTIPHLOGISTIC, ANTITHROMBOTIC | BOEHRINGER INGELHEIM GMBH (DE) | 1980-01-08 | — | — | US | disclosed |