Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484639 | 0.88 | KDM4E (0.49) | MEN1KMT2ARXFP1L3MBTL1ADORA2A | |
| SCHEMBL11361940 | 0.87 | ADORA2A (0.50) | MEN1KMT2ARXFP1L3MBTL1ADORA2A | |
| SCHEMBL11485485 | 0.87 | ADORA2A (0.50) | MEN1KMT2ARXFP1L3MBTL1ADORA2A | |
| SCHEMBL11486783 | 0.86 | MAPT (0.50) | RXFP1L3MBTL1ADORA2AADORA1MAPK1 | |
| SCHEMBL11490087 | 0.85 | MET (0.52) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11354056 | 0.85 | KDM4E (0.54) | L3MBTL1ADORA2AMAPK1ALDH1A1KDM4E | |
| SCHEMBL11357456 | 0.83 | ALDH1A1 (0.49) | MEN1KMT2AL3MBTL1ADORA2AADORA1 | |
| SCHEMBL11490906 | 0.83 | L3MBTL1 (0.40) | MEN1KMT2ARXFP1L3MBTL1ADORA2A | |
| SCHEMBL11490910 | 0.83 | L3MBTL1 (0.40) | MEN1KMT2ARXFP1L3MBTL1ADORA2A | |
| SCHEMBL11484494 | 0.83 | L3MBTL1 (0.40) | MEN1KMT2ARXFP1L3MBTL1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224322-A | ANTICOAGULANTS, ANTIPHLOGISTICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4182887-A | ANTIPHLOGISTIC, ANTITHROMBOTIC | BOEHRINGER INGELHEIM GMBH (DE) | 1980-01-08 | — | — | US | disclosed |