Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495212 | 0.87 | CES1 (0.55) | CES1SRCNPC1RAB9ALMNA | |
| SCHEMBL11483700 | 0.85 | CES1 (0.53) | CES1NPC1RAB9ACYP2C19MAPK1 | |
| SCHEMBL9860776 | 0.84 | CES1 (0.64) | CES1SRCRAB9ALMNAHIF1A | |
| SCHEMBL3266492 | 0.81 | CES1 (0.65) | CES1SRCLMNAKCNN4TDP1 | |
| SCHEMBL11171387 | 0.80 | CES1 (0.58) | CES1SRCLMNATDP1MAPK1 | |
| SCHEMBL11080785 | 0.80 | CES1 (0.57) | CES1SRCLMNAKIF11HIF1A | |
| SCHEMBL3272321 | 0.80 | CES1 (0.57) | CES1SRCRAB9ALMNAKIF11 | |
| SCHEMBL36702 | 0.79 | CES1 (0.66) | CES1SRCNPC1LMNAHIF1A | |
| SCHEMBL9065321 | 0.79 | CES1 (0.66) | CES1SRCNPC1LMNAHIF1A | |
| SCHEMBL11295018 | 0.79 | CES1 (0.57) | CES1SMN1; SMN2CHRM2CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190602-A | PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |